Perineural Injection Therapy (PIT) was developed by New Zealander Dr. John Lyftogt. It is a safe and effective treatment for painful conditions arising from the musculoskeletal system. Neural Prolotherapy is sometimes referred to as Perineural Injection Treatment. It involves first making an accurate diagnosis of the cause of pain. This type of pain is typically due to an injured and non-healing sensory nerve causing pain, inflammation and delayed healing.